ABSTRACT

Selenium (Se), is a vital trace element required by many living organisms. It is mainly incorporated in selenoproteins functioning in boosting immune system, reducing inflammation, decreasing cardiovascular disease and inhibiting cancer progression. Fifty different selenoprotein families have been identified. They fulfill a broad range of physiological roles, notably functioning as antioxidants and participating in thyroid hormone metabolism. They are key regulators of stress responses, metabolism, and immunity. Selenoproteins will may be utilized in the treatment of various pathologies, including cancer, diabetes mellitus, neurodegenerative disorders, and cardiovascular injuries, in the near future. This technical report will provide a general overview of selenoproteins and their functions.